Fragile Please Handle with Care shipping labels communicate that your shipment or package needs to be handled with evtreme care and attention. Red on white labels help your message stand out from the rest or the cardboard box. These FRAGILE labels help insure your package gets handled properly. Proper warning labels, like these, have an aggressive acrylic adhesive that is specifically formulated to adhere to cardboard boxes, packing list envelopes and industrial steel or plastic drums. These attention getting labels are positioned on a peel-off liner and are continuously positioned side to side on a roll of 500 labels.